Title: How Many Distinct Words Can Be Formed from "BIOINFORMATICS" With All Vowels Together?


Introduction

Understanding the Context

The word BIOINFORMATICS is a rich and challenging Latin-derived term packed with consonants and vowels, making it a fascinating puzzle for combinatorial enthusiasts and language lovers alike. A commonly asked question is: How many distinct words can be formed using all the letters in "BIOINFORMATICS" if all vowels must appear together?

In this article, we explore this intriguing linguistic problem from both a mathematical and practical perspective, breaking down the step-by-step process to calculate the number of unique arrangements where all vowels appear as a contiguous block.


Understanding the Word Structure

Key Insights

The word BIOINFORMATICS contains 16 letters, including:

  • Vowels: I, O, I, I, A (5 vowels: I ×3, O ×1, A ×1)
    - Consonants: B, N, F, R, M, T, C, S (11 consonants)

Our goal is to arrange all 16 letters such that the five vowels occur together as a single group, preserving their internal order possibilities (since the vowels can repeat), while treating this block as a single “super-letter.”


Step 1: Treat the Vowel Block as a Single Unit

Final Thoughts

Because the five vowels must appear consecutively, we treat them as one combined unit or "super-letter." This reduces the problem from arranging 16 letters to arranging:

  • 1 vowel block
    - 11 consonants

Total objects to arrange = 1 (vowel block) + 11 consonants = 12 items


Step 2: Count Arrangements of the 12 Units

However, these 12 units include both consonants and repeated letters, so we must account for duplicates:

  • Among the 11 consonants: B, N, F, R, M, T, C, S — all distinct
    So the consonant collection has no internal repetition.

  • The vowel block contains repeated letters: I appears 3 times, O once, A once

Thus, we are arranging 12 positions in which:
- 11 objects (consonants) are distinct
- The vowel block is treated as one unit
- Within the vowel block, the 5 vowels include repetitions